Drug interactions are reported among people who take Aleve and Tramadol together. Also, he didn't replace it with anything. I was taken off Depakote cold turkey and experienced a nervous breakdown. But even this amount can harm some people’s livers, so aim for no more than 3,000 mg per day.For children under the age of 12, it’s best to check with their healthcare provider to determine the safest dose for their body weight.Keep in mind that many OTC medications contain acetaminophen in a variety of doses, usually 325 mg, 500 mg, or 650 mg. This enzyme is involved in metabolizing over 60% of drugs.Doctors use CYP450 to gauge the appropriate dosages of medications based on the processing time it takes for the drugs to be active in the system. This has caused a significant amount of research to prove CBD’s legitimacy and place in the medical industry. Advil is one of the most commonly purchased over the counter medicines. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.These medications may interact and cause very harmful effects. In this case, it’s better to alternate when you take each medication. These medications are not usually taken together. This means that prescribed drugs can have a slower time to metabolize, ultimately affecting how your body takes in those drugs. Try searching for what you seek or The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 2) Advil.