NizoralStore at controlled room temperature 15°–25°C (59°–77°F).Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.These are not all the possible side effects of NizoralCall your doctor for medical advice about side effects. These elevated plasma concentrations may increase or prolong both therapeutic and adverse effects of these drugs. Similarly, ketoconazole may modify the pharmacokinetics of other substances that share this metabolic pathway. and the side effects of Derinide (100mcg) are May lead to Peptic ulceration, Osteoporosis, Ocular hypertension, Cushing like features, Suppression of adrenal function.. Hepatotoxicity has been reported with restarting oral ketoconazole (rechallenge). Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.This is not an exhaustive list of possible drug interactions. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. The major route of excretion is through the bile into the intestinal tract with about 57% being excreted in the feces.In patients with hepatic or renal impairment, the overall pharmacokinetics of ketoconazole was not significantly different when compared with healthy subjects.Limited pharmacokinetic data are available on the use of NizoralMeasurable ketoconazole plasma concentrations have been observed in pre-term infants (single or daily doses of 3 to 10 mg/kg) and in pediatric patients 5 months of age and older (daily doses of 3 to 13 mg/kg) when the drug was administered as a suspension, tablet or crushed tablet. Please note for the minimum order for Exports is of US$ 100. It is, therefore, advisable to monitor digoxin concentrations in patients receiving ketoconazole.Telithromycin: A multiple-dose interaction study with ketoconazole showed that CCilostazol: Concomitant administration of single doses of cilostazol 100 mg and ketoconazole 400 mg approximately doubled cilostazol concentrations and altered (increase/decrease) the concentrations of the active metabolites of cilostazol.Coumarins: Ketoconazole may enhance the anticoagulant effect of coumarin-like drugs, thus the anticoagulant effect should be carefully titrated and monitored.Dabigatran: In patients with moderate renal impairment (CrCL 50 mL/min to ≤ 80 mL/min), consider reducing the dose of dabigatran to 75 mg twice daily when it is coadministered with ketoconazole.Ergot alkaloids: The potential increase in plasma concentrations of ergot alkaloids when coadministered with NizoralEletriptan: Eletriptan should be used with caution with ketoconazole, and specifically, should not be used within at least 72 hours of treatment with ketoconazole.Irinotecan: The potential increase in plasma concentrations of irinotecan when coadministered with NizoralDocetaxel: In the presence of ketoconazole, the clearance of docetaxel in cancer patients was shown to decrease by 50%.Alprazolam, midazolam, triazolam: Coadministration of NizoralPimozide: The potential increase in plasma concentrations of pimozide when coadministered with NizoralAripiprazole: Coadministration of ketoconazole (200 mg/day for 14 days) with a 15 mg single dose of aripiprazole increased the AUC of aripiprazole and its active metabolite by 63% and 77%, respectively. All the risks and benefits should be discussed with the doctor before using this medicine.This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Tên đơn vị: CÔNG TY CỔ PHẦN TRUNG TÂM CHĂM SÓC SỨC KHỎE CỘNG ĐỒNG CHAC Người đại diện pháp luật: Ngô Hớn Đình