This document does not contain all possible interactions from the use of this medication. These drugs work to restore the balance of chemicals in the brain that have caused depression. Venlafaxine has mild interactions with at least 35 different drugs. All of her vital signs returned to normal within eight hours.

Effexor, the brand name of the drug venlafaxine, treats depression, anxiety and panic disorders. These herbs can interact with the drug, modifying its effects, which can result in adverse reactions or failure of the drug completely.In 2004, a report released in the American Journal of Psychiatry indicated that a 40 year old woman collapsed one hour after taking a prescribed dose of venlafaxine alongside a dose of sour date nut (Ziziphus jujube), given to her by a traditional Chinese medicine practitioner. She has written veterinarian articles for and private clients. Yohimbine may also interact with other norepinephrine reuptake inhibitors, such as tricyclic antidepressants, and serotonin- norepinephrine reuptake inhibitors, including clomipramine (Anafranil), desvenlafaxine (Pristiq), duloxetine (Cymbalta), imipramine (Tofranil), milnacipran (Savella), and venlafaxine (Effexor). Summary: Drug interactions are reported among people who take Effexor and Vitamins together. The study is created by eHealthMe based on reports of 1,264 people who take Effexor and Vitamins from the FDA, and is updated regularly. They also caution that 5-HTP can interfere with many other types of antidepressants including SSRIs, and Tricyclics. The woman experienced nausea, severe dizziness and profuse sweating. As a result, doctors caution strongly against using St. John's Wort in conjunction with venlafaxine.Griffonia (Griffonia simplicifolia) contains a substance known as 5-Hydroxytryptophan, or 5-HTP. Due to its mode of action, some herbs and compounds should be avoided while using venlafaxine. Interactions: Assuming you are taking "normal" levels of vitamins, I wasn't able to find any potential interactions between vitamins and either effexor (venlafaxine ... Read More 1 doctor agrees According to the University of Maryland Medical Center, 5-HTP can help with mood swings, anxiety and depression. Some reports may have incomplete information.Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. After this incident, doctors caution against the use of sour date nut alongside venlafaxine.The University of Michigan indicates that St. John's Wort (Hypericum perforatum) should be avoided while taking venlafaxine, but mentions that there are no current reports of a negative interaction with this particular drug. Though scientists hypothesize that St. John's Wort works like most antidepressant medications available, studies are still conflicting, and the latest findings from the Vanderbilt University School of Medicine indicate that St. John's Wort is "not a benign treatment," due to the number of incidents in which it has interacted with other drugs in negative ways. See 'Serotonin syndrome' and 'Monoamine-oxidase inhibitor' under Antidepressant drugs in BNF for more information and for specific advice on avoiding monoamine-oxidase inhibitors during and after administration of other serotonergic drugs. There are also hundreds of drugs which are known to interact with Tofranil in major, moderate, or mild ways, so let your doctor know what other medications you are taking before you begin taking the medication.