Other drugs may interact with spironolactone, including prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Aldactone only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. Spironolactone may worsen kidney function in patients with low to no salt in their body or in those who take other blood pressure medicines (eg, ARB, ACE inhibitor). You must continue to take it as directed if you expect to lower your blood pressure and keep it down. Worsening of renal function can also occur with concomitant use of nephrotoxic drugs (e.g., aminoglycosides, cisplatin, and NSAIDs). Spironolactone causes increased amounts of sodium and water to be excreted, while potassium is retained. Spironolactone is also used to lessen the need for hospitalization for heart failure.Spironolactone is also used to diagnose and treat hyperaldosteronism, a condition in which the adrenal gland produces too much hormone called aldosterone.
Clinical classification of heart disease may worsen with pregnancy and lead to maternal death. In patients with hypertension, decreases in systolic blood pressure have been observed at doses ranging from 25 to 100 mg/day. You may report side effects to FDA at 1-800-FDA-1088.Using Aldactone with other drugs that make you dizzy can worsen this effect. Patients who were intolerant of the initial dosage regimen had their dose decreased to one 25 mg tablet every other day at one to four weeks.
Aldactone 100 mg (ALDACTONE 100 SEARLE 1031) Edematous states in which secondary aldosteronism is usually involved include congestive heart failure, hepatic cirrhosis, and nephrotic syndrome.
These conditions may cause you to lose too much water or salt and may lead to low blood pressure. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of this medicine, take it as soon as possible. Make sure you tell your doctor if you have any other medical problems, especially:In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, Many patients who have high blood pressure will not notice any signs of the problem.
Doses greater than 100 mg/day generally do not provide additional reductions in blood pressure Aldactone 25 mg tablets are round, light yellow, film-coated, with SEARLE and 1001 debossed on one side and Aldactone and 25 on the other side, supplied as:Aldactone 50 mg tablets are oval, light orange, scored, film-coated, with SEARLE and 1041 debossed on the scored side and Aldactone and 50 on the other side, supplied as:Aldactone 100 mg tablets are round, peach-colored, scored, film-coated, with SEARLE and 1031 debossed on the scored side and Aldactone and 100 on the other side, supplied as:Patients who receive Aldactone should be advised to avoid potassium supplements and foods containing high levels of potassium, including salt substitutes.This product's label may have been updated. Spironolactone also reduced the risk of hospitalization for cardiac causes (defined as worsening heart failure, angina, ventricular arrhythmias, or myocardial infarction) by 30% (p <0.001; 95% confidence interval 18% to 41%).The survival curves by treatment group are shown in Figure 1.Mortality hazard ratios for some subgroups are shown in Figure 2. The favorable effect of spironolactone on mortality appeared similar for both genders and all age groups except patients younger than 55.
Tell any doctor who treats you that you are using Aldactone.If you need surgery, tell your surgeon you currently use this medicine. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Safety and efficacy have not been established.Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of spironolactone in the elderly. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body. Monitor BUN, serum creatinine, and electrolytes prior to and periodically during therapy. On its own, spironolactone is only a weak diureticbecause it primarily t…