It should simply be used with There are several guidelines for prescribing amiodarone.
Increased sensitivity to sunlight is often seen. Typical maintenance doses are approximately 200 mg daily and in non-urgent situations it may well be appropriate to start the patient on this dose.
Elimination half-life average of 58 days (ranging from 25–100 days [Remington: The Science and Practice of Pharmacy 21st edition]) for amiodarone and 36 days for the active metabolite, desethylamiodarone (DEA) [Package Insert- Pacerone(R)]. Again, sotalol and other beta blockers do have the advantage of slowing the ventricular response even if reversion does not occur.Three large randomised trials of chronic therapy for paroxysmal/persistent atrial fibrillation have convincingly shown amiodarone to be significantly superior to sotalol and propafenone (a close relative of flecainide). While amiodarone has many pharmacological effects, it also has many adverse effects. There is some evidence of synergy between beta blockers and amiodarone in terms of efficacy against tachyarrhythmias and the combination is not necessarily contraindicated. Both drugs are significantly more effective than placebo. To order, contact In these cases, amiodarone can be used regardless of the individual's underlying heart function and the type of ventricular tachycardia; it can be used in individuals with So-called 'acute onset atrial fibrillation', defined by the North American Society of Pacing and Electrophysiology (NASPE) in 2003, responds well to short duration treatment with amiodarone. The dose of amiodarone administered is tailored to the individual and the dysrhythmia that is being treated. In some patients (for example the elderly), it is worth trying to reduce further to 100 mg/day after 2-3 months at 200 mg/day. Amiodarone can cause bradyarrhythmias and this effect will be enhanced by co-administration with beta blockers, verapamil or diltiazem.