If they’re more severe or don’t go away, talk to your doctor or pharmacist.Call your doctor right away if you have serious side effects. A) and halve the tablet by pressing down and away from the score-line so that the tablet opens at the score-line side. • Prevention of depressive episodes in patients with bipolar I disorder who experience predominantly depressive episodes (see section 5.1).Lamotrigine is not indicated for the acute treatment of manic or depressive episodes.Lamotrigine tablets should be swallowed whole. Common findings include fever, hepatosplenomegaly, rash, lymphadenopathy, neurologic symptoms, cytopenias, high serum ferritin, hypertriglyceridemia, and liver function and coagulation abnormalities. A typical adult dose may cause drug levels in your body to be higher than normal.