Suprax is an orally active cephalosporin antibiotic which has marked It is indicated for the treatment of the following acute infections when caused by susceptible micro-organisms:Clinical efficacy has been demonstrated in infections caused by commonly occuring pathogens including The usual course of treatment is 7 days.

Caution should be exercised with regard to activities requiring alertness and fine motor coordination, such as driving, piloting aircraft, operating machinery, and deep-sea diving, while symptoms persist.Mefloquine may increase the risk of convulsions in patients with epilepsy. You may get serious heart problems that can lead to death. Because these adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to Mefloquine exposure.The most frequently reported adverse reactions are nausea, vomiting, loose stools or diarrhea, abdominal pain, dizziness or vertigo, loss of balance, and neuropsychiatric events such as headache, somnolence, and sleep disorders (insomnia, abnormal dreams). Protein binding is about 98%.Mefloquine crosses the placenta. However, you should not flush this medication down the toilet.

There is evidence that Mefloquine is excreted mainly in the bile and feces. Mefloquine should be used with caution in patients with a previous history of depression. Cases of suicidal ideation and suicide have been reported.

Mefloquine is in a class of medications called antimalarials. The bioavailability of the tablet formation compared with an oral solution was over 85%. If a second dose is not tolerated, the patient should be monitored closely and alternative malaria treatment considered if improvement is not observed within a reasonable period of time (see Clinical studies of Mefloquine did not include sufficient numbers of subjects aged 65 and older to determine whether they respond differently from younger subjects.

Because the studies in humans cannot rule out the possibility of harm, Mefloquine should be used during pregnancy only if clearly needed.Published data on Mefloquine use during pregnancy include randomized controlled trials, intervention trials, prospective and retrospective cohort studies, and case series. We’ll send you a link to a feedback form.

There is one report of cardiopulmonary arrest, with full recovery, in a patient who was taking a beta blocker (propranolol) (see Halofantrine should not be administered with Mefloquine or within 15 weeks of the last dose of Mefloquine due to the risk of a potentially fatal prolongation of the QTc interval (see Concomitant administration of Mefloquine and other related antimalarial compounds (e.g., quinine, quinidine and chloroquine) may produce electrocardiographic abnormalities and increase the risk of convulsions (see Co-administration of a single 500 mg oral dose of Mefloquine with 400 mg of ketoconazole once daily for 10 days in 8 healthy volunteers resulted in an increase in the mean Cmax and AUC of Mefloquine by 64% and 79%, respectively, and an increase in the mean elimination half-life of Mefloquine from 322 hours to 448 hours.

In these cases, the drug should be discontinued and an alternative medication should be submitted.Neurologic symptoms such as dizziness or vertigo, tinnitus, and loss of balance have been reported. If you vomit again after taking the extra dose, call your doctor.This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.Unless your doctor tells you otherwise, continue your normal diet.Take the missed dose as soon as you remember it.

Lower Cost Alternative. • For specific information regarding your prescription benefit coverage and copay information, please visit . See the FDA's Safe Disposal of Medicines website (It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily.

Mefloquine is a member of the antimalarial quinolines drug class and is commonly used for Malaria and Malaria Prevention. Monitor cardiac function (if possible by ECG) and neuropsychiatric status.

There are no specific antidotes. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. This publication is available at https://www.gov.uk/government/publications/mefloquine-advice-service-for-former-and-serving-personnel/mefloquine-advice-service-for-former-and-serving-personnel Normal dose and schedule may be given in patients with creatinine clearances of 20 ml/min or greater. Thereafter, plasma levels of the main metabolite and Mefloquine declined at a similar rate. Experiments conducted in vitro with human blood using concentrations between 50 and 1000 mg/mL showed a relatively constant erythrocyte-to-plasma concentration ratio of about 2 to 1. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.

Patients should be instructed to read the Medication Guide when Mefloquine is received and to carry the information wallet card with them when they are taking Mefloquine.