Interaction studies have only been performed in adults.

Theamount excreted asunchangedactivesubstanceis estimated to be about 4-6% of thedose,administered asAfterasingle doseof OmnicOcas 0,4 mgand insteadystate, elimination half-lives ofabout 19 and 15 hours, respectively, havebeen measured.Single and repeat dosetoxicitystudies wereperformed in mice, rats and dogs.Inaddition, reproduction toxicityin rats, carcinogenicityin miceand rats andThegeneral toxicityprofile, as seen withhigh doses of tamsulosin,is consistent with theknown pharmacologicalactions of theα-adrenoceptor antagonists.At veryhigh doselevelsthe ECG was altered in dogs.

(םייגרוריכ חותינ ינפל הפורתב םייניעב טקרטקפ םוהיזב לופיטל תופורת :אמגודל יתירט לוזנוקרטיא ,לוזנוקוטק תיחופלש ךותל ) ןתשה רוחאל הטילפ וא ( הכיפשה חפנ דרוי וא םלענכיה לע עיפשמ תושרודה תונוכמ תלעפהל וא גוהנל תלו .תונריע תלעפהב וא/ו הגיהנב רהזיהל ךילע ןכ לעו ,תרוחרחסל םורגל לולע .תונריע תשרוד רשא תונוכמו ןונימה :אוה ללכ ךרדב לבוקמה ןונימה .דבלב אפורה ידי לע ועבקי לופיטה ןפוא םימ טעמ םע התומלשב הפורתה תא עולבל !

It is metabolised in the liver. Most tamsulosin is present in plasma in the form of unchanged active substance. Always consultyour doctor, ifyou consider stoppingthis therapy.Ifyou haveanyfurther questions on theuse of this product, askyour doctor orpharmacist.Likeallmedicines, OmnicOcascan cause sideeffects, although noteverybodygets them.Common (less than 1 in 10, morethan 1 in 100 (1-10%)):Dizziness, particularlywhen goingto sit or standup.Abnormal ejaculation(ejaculation disorder).Thismeans that semen does not leavethe bodyvia theurethra, but instead goes into the bladder(retrogradeejaculation) orthe ejaculationvolumeis reduced orabsent (ejaculation failure).This phenomenon isharmless.Uncommon (morethan 1in 1000, less than 1 in 100 (0,1-1%)):Headache, palpitations(the heart beats morerapidlythan normaland itis also noticeable),reduced blood pressuree.g. If this does not help then volume expanders and, when necessary, vasopressors could be employed. Tamsulosin binds selectively and competitively to the postsynaptic α. the throat or tongue), difficultbreathingand / or itchingand rash- ifyou sufferfrom faintingdueto reduced blood pressurewhen changingposture- Periodicmedical examinations arenecessaryto monitorthe development of the- Rarely, faintingcan occur duringtheuse of OmnicOcas,as withothermedicinalproducts of this type.At the first signs of dizziness orweaknessyou should sit or lie- Ifyou suffer from severekidneyproblems, tellyourdoctor.- Ifyou areundergoingorhavebeen scheduledforeyesurgerybecause ofcloudiness ofthe lens (cataract)orincreased pressurein theeye(glaucoma). At the first signs of orthostatic hypotension (dizziness, weakness), the patient should sit or lie down Before therapy with Omnic Ocas 0,4 is initiated, the patient should be examined in order to exclude the presence of other conditions, which can cause the same symptoms as benign prostatic hyperplasia. The recommended dose is 5mg Solifenacin succinate once daily. You should check withyourdoctor orpharmacistifyou arenot sure. Ifyoustop taking Omnic Ocas. Tamsulosin hydrochloride should not be given in combination with strong inhibitors of CYP3A4 in patients with poor Tamsulosin hydrochloride should be used with caution in combination with strong and moderate Concomitant administration of tamsulosin hydrochloride with paroxetine, a strong inhibitor of CYP2D6, resulted in a Cmax and AUC of tamsulosin that had increased by a factor of 1.3 and 1.6, respectively, but these increases are not considered clinically relevant -adrenoceptor antagonists could lead to hypotensive effects. The Price Of Omnic Ocas. At thefirst signs of orthostatichypotension (dizziness, weakness), thepatient should sit or liedown untilthe symptomshavedisappeared.Beforetherapywith Omnic Ocas 0,4 is initiated, thepatient should be examined in orderto exclude thepresenceof other conditions,whichcan cause thesamesymptoms asbenign prostatichyperplasia. In rats, hardly any induction of microsomal liver enzymes was seen to be caused by tamsulosin.

Dosage and Administration. whengettingup quicklyfrom aseatingor lyingpositionsometimes associated with dizziness; runnyor blocked nose(rhinitis), diarrhoea, feelingsickand vomiting,constipation, weakness(asthenia), rashes, itchingand hives (urticaria).Rare(morethan 1 in 10,000, less than 1 in 1000 (0,01-0,1%)):Faintness and sudden local swellingof thesoft tissues ofthe body(e.g.

Read the package leaflet before use. Omnic Ocas Generfarma is an alpha-blocker.

Because these spontaneously reported events are from the worldwide post marketing experience, the frequency of events and the role of tamsulosin in their causation cannot be Acute overdose with 5 mg tamsulosin hydrochloride has been reported.